Ephrin A5 Protein (EFNA5) (Fc Tag)

Produktnummer ABIN7318439

Dieses Recombinant Ephrin A5-Protein wird in Human Cells exprimiert.

Kurzübersicht für Ephrin A5 Protein (EFNA5) (Fc Tag) (ABIN7318439)

Target: Ephrin A5 (EFNA5)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Ephrin A5 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human Ephrin-A5/EFNA5 Protein (Fc Tag)

Sequenz: Gln21-Asn203

Produktmerkmale: Recombinant Human Ephrin-A5 is produced by our Mammalian expression system and the target gene encoding Gln21-Asn203 is expressed with a Fc tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Ephrin A5 (EFNA5)

Andere Bezeichnung: Ephrin-A5/EFNA5

Hintergrund:

Background: Ephrin-A5 (EFNA5) belongs to the ephrin family,contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-A5 is a cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.

Synonym: Ephrin-A5,EPLG7, LERK7,EFNA5,LERK-7,EPH-related receptor tyrosine kinase ligand 7,AL-1

Molekulargewicht: 48.3 kDa

UniProt: P52803

Pathways: RTK Signalweg