M-CSF/CSF1 Protein
Kurzübersicht für M-CSF/CSF1 Protein (ABIN7320618)
Target
Alle M-CSF/CSF1 (CSF1) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Verwendungszweck
- Recombinant Mouse M-CSF/CSF1 Protein (Active)
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Sequenz
- Lys33-Glu262
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Produktmerkmale
- Recombinant Mouse Macrophage colony-stimulating factor 1 is produced by our Mammalian expression system and the target gene encoding Lys33-Glu262 is expressed.
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Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
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Biological Activity Comment
- Measured in a cell proliferation assay using M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 0.04-0.2 ng/ml.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 0.
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
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Andere Bezeichnung
- M-CSF/CSF1
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Hintergrund
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Background: Macrophage colony-stimulating factor 1(M-csf)is a single-pass type I membrane protein . It is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
Synonym: Macrophage colony-stimulating factor 1,CSF-1,MCSF,Csf1,Csfm
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Molekulargewicht
- 26.0 kDa
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UniProt
- P07141
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Pathways
- RTK Signalweg
Target
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