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M-CSF/CSF1 Protein

Recombinant M-CSF/CSF1-Protein exprimiert in Human Cells.
Produktnummer ABIN7320618

Kurzübersicht für M-CSF/CSF1 Protein (ABIN7320618)

Target

Alle M-CSF/CSF1 (CSF1) Proteine anzeigen
M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 33
  • 19
  • 6
  • 1
Maus

Quelle

  • 20
  • 20
  • 7
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Human Cells

Reinheit

> 95 % as determined by SDS-PAGE
  • Verwendungszweck

    Recombinant Mouse M-CSF/CSF1 Protein (Active)

    Sequenz

    Lys33-Glu262

    Produktmerkmale

    Recombinant Mouse Macrophage colony-stimulating factor 1 is produced by our Mammalian expression system and the target gene encoding Lys33-Glu262 is expressed.

    Endotoxin-Niveau

    < 1.0 EU per μg as determined by the LAL method.

    Biological Activity Comment

    Measured in a cell proliferation assay using M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 0.04-0.2 ng/ml.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 0.

    Lagerung

    4 °C,-20 °C,-80 °C

    Informationen zur Lagerung

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

    Andere Bezeichnung

    M-CSF/CSF1

    Hintergrund

    Background: Macrophage colony-stimulating factor 1(M-csf)is a single-pass type I membrane protein . It is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.

    Synonym: Macrophage colony-stimulating factor 1,CSF-1,MCSF,Csf1,Csfm

    Molekulargewicht

    26.0 kDa

    UniProt

    P07141

    Pathways

    RTK Signalweg
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