Cathepsin B Protein (CTSB) (His tag)

Produktnummer ABIN7320464

Dieses Recombinant Cathepsin B-Protein wird in Human Cells exprimiert.

Kurzübersicht für Cathepsin B Protein (CTSB) (His tag) (ABIN7320464)

Target: Cathepsin B (CTSB)

Protein-Typ: Recombinant

Spezies: Maus

Quelle: Human Cells

Reinheit: > 95 % as determined by SDS-PAGE

Produktdetails

Aufreinigungstag / Konjugat: Dieses Cathepsin B Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse Cathepsin B/CTSB Protein (His Tag)

Sequenz: His18-Phe339

Produktmerkmale: Recombinant Mouse Cathepsin B is produced by our Mammalian expression system and the target gene encoding His18-Phe339 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Cathepsin B (CTSB)

Andere Bezeichnung: Cathepsin B/CTSB

Hintergrund:

Background: Cathepsin B (CatB) is an enzymatic protein belonging to the peptidase (or protease) families. It is the first described member of the family of lysosomal cysteine proteases. It is known to process a number of proteins, including pro and active caspases, prorenin and secretory leucoprotease inhibitor (SLPI). It is believed to participate in intracellular degradation and turnover of proteins. Cathepsin B may play a role in activation and inactivation of caspases, activation of renin and inactivation of SLPI, the key steps in apoptosis, angiotensin production, and progression of emphysema, respectively. Cathepsin B may also have a role in invasion and metastasis.

Synonym: Cathepsin B,Ctsb,Cathepsin B1

Molekulargewicht: 36.4 kDa

UniProt: P10605

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades