Arylsulfatase A Protein (ARSA) (His tag)

Produktnummer ABIN7318179

Recombinant Arylsulfatase A-Protein exprimiert in Human Cells.

Kurzübersicht für Arylsulfatase A Protein (ARSA) (His tag) (ABIN7318179)

Target: Arylsulfatase A (ARSA)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Arylsulfatase A Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Arylsulfatase A/ARSA Protein (His Tag)

Sequenz: Arg19-Ala507

Produktmerkmale: Recombinant Human Arylsulfatase A is produced by our Mammalian expression system and the target gene encoding Arg19-Ala507 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.5.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: Arylsulfatase A (ARSA)

Andere Bezeichnung: Arylsulfatase A/ARSA

Hintergrund:

Background: Arylsulfatase A (ARSA) is a lysosomal enzyme that breaks down Cerebroside 3-Sulfate, a major constituent of the myelin sheet, into Cerebroside and Sulfate. The ARSA deficiency results in Metachromatic Leukodystrophy (MLD), a lysosomal storage disease in the central and peripheral nervous systems with severe and progressive neurological symptoms. Recombinant Human ARSA corresponds to the ARSA mature peptide and has sulfatase activity.

Synonym: Arylsulfatase A, ASA, Cerebroside-Sulfatase, ARSA

Molekulargewicht: 52.9 kDa

UniProt: P15289