Gastrin-Releasing Peptide Protein (GRP) (AA 24-50) (Fc Tag)

Produktnummer ABIN7092808

Dieses Recombinant Gastrin-Releasing Peptide-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für Gastrin-Releasing Peptide Protein (GRP) (AA 24-50) (Fc Tag) (ABIN7092808)

Target: Gastrin-Releasing Peptide (GRP)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Applikation: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Produktdetails

Proteineigenschaft: AA 24-50

Aufreinigungstag / Konjugat: Dieses Gastrin-Releasing Peptide Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human GRP with C-terminal human Fc tag

Spezifität: GRP(Val24-Met50) hFc(Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Anwendungsinformationen

Applikationshinweise: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Kommentare:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: Gastrin-Releasing Peptide (GRP)

Andere Bezeichnung: GRP

Hintergrund: BN,GRP-10,preproGRP,proGRP
This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C. These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

Molekulargewicht: predicted molecular mass of 29.0 kDa after removal of the signal peptide. The apparent molecular mass of GRP-hFc is 25-35 kDa due to glycosylation.

UniProt: P07492

Pathways: Peptide Hormone Metabolism, Hormone Activity