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IL21 Receptor Protein (Interleukin 21 Receptor) (mFc Tag)

IL21R Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 %
Produktnummer ABIN7092744
$435.38
Zzgl. Versandkosten $45.00
Lieferung in 9 bis 11 Werktagen
  • Target Alle IL21 Receptor (IL21R) Proteine anzeigen
    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
    Protein-Typ
    Recombinant
    Spezies
    • 12
    • 6
    • 1
    • 1
    Human
    Quelle
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses IL21 Receptor Protein ist gelabelt mit mFc Tag.
    Sequenz
    IL21R(Cys20-Glu232)+mFc(Pro99-Lys330)
    Produktmerkmale
    Tagged Protein: C-Mouse Fc Tag
    Aufreinigung
    affinity purification
    Reinheit
    > 95 %
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    Haltbarkeit
    12 months
  • Target
    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
    Andere Bezeichnung
    IL21R (IL21R Produkte)
    Synonyme
    IL21R, il-21ra.a, CD360, NILR, interleukin 21 receptor, interleukin 21 receptor, tandem duplicate 1, IL21R, il21r.1, Il21r
    Hintergrund
    Synonymes: CD360, IMD56, NILR
    Description: The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.
    Molekulargewicht
    55-70 kDa
    UniProt
    Q9HBE5
    Pathways
    JAK-STAT Signalweg
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