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ROR1 Protein (Receptor Tyrosine Kinase-Like Orphan Receptor 1) (AA 30-403) (Fc Tag,FITC)

ROR1 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Produktnummer ABIN6973213
$2,386.15
Zzgl. Versandkosten $45.00
Lieferung in 5 Werktagen
  • Target Alle ROR1 Proteine anzeigen
    ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 30-403
    Spezies
    • 30
    • 8
    • 8
    • 8
    • 3
    • 1
    • 1
    Human
    Quelle
    • 26
    • 7
    • 5
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses ROR1 Protein ist gelabelt mit Fc Tag,FITC.
    Produktmerkmale
    FITC-Labeled Human ROR1 Protein, Fc Tag
    Reinheit
    >90 % as determined by SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Lagerung
    -20 °C
  • Target
    ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
    Andere Bezeichnung
    ROR1 (ROR1 Produkte)
    Synonyme
    NTRKR1, dJ537F10.1, 2810404D04Rik, Ntrkr1, mRor1, RGD1559469, ROR1, fi34e02, si:dkey-209n16.1, wu:fi34e02, receptor tyrosine kinase like orphan receptor 1, receptor tyrosine kinase-like orphan receptor 1, ROR1, Ror1, ror1
    Hintergrund
    Tyrosine-protein kinase transmembrane receptor ROR1 is also known as Neurotrophic tyrosine kinase, receptor-related 1 (NTRKR1), which belongs to the protein kinase superfamily or tyr protein kinase family or ROR subfamily. ROR1 contains 1 FZ (frizzled) domain, 1 Ig-like C2-type (immunoglobulin-like) domain, 1 kringle domain, 1 protein kinase domain. ROR1 is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. ROR1 could interact with casein kinase 1 epsilon (CK1ε) to activate phosphoinositide 3-kinase-mediated AKT phosphorylation and cAMP-response-element-binding protein (CREB), which was associated with enhanced tumor-cell growth.
    Molekulargewicht
    68.6 kDa
    Pathways
    RTK Signalweg, WNT Signalweg, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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