Ret Proto-Oncogene Protein (RET) (Fc Tag)
-
- Target Alle Ret Proto-Oncogene (RET) Proteine anzeigen
- Ret Proto-Oncogene (RET)
- Protein-Typ
- Recombinant
-
Spezies
- Human
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Ret Proto-Oncogene Protein ist gelabelt mit Fc Tag.
- Sequenz
- RET (Leu29-Arg635)+hFc(GLU99-ALA330)
- Produktmerkmale
- Tagged Protein: C-Human Fc tag
- Aufreinigung
- affinity purification
- Top Product
- Discover our top product RET Protein
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Konservierungsmittel
- Without preservative
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
- Haltbarkeit
- 12 months
-
- Target
- Ret Proto-Oncogene (RET)
- Andere Bezeichnung
- RET (RET Produkte)
- Synonyme
- c-ret Protein, cret Protein, etID315074.13 Protein, ret1 Protein, wu:fd13h01 Protein, X-ret Protein, ret-A Protein, xret Protein, RET Protein, MTC1 Protein, CDHF12 Protein, CDHR16 Protein, HSCR1 Protein, MEN2A Protein, MEN2B Protein, PTC Protein, RET-ELE1 Protein, RET51 Protein, RET9 Protein, c-Ret Protein, ret proto-oncogene receptor tyrosine kinase Protein, ret proto-oncogene S homeolog Protein, ret proto-oncogene Protein, ret Protein, ret.S Protein, RET Protein, Ret Protein
- Hintergrund
-
Synonymes: CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1
Description: This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related proteins to the encoded receptor stimulates receptor dimerization and activation of downstream signaling pathways that play a role in cell differentiation, growth, migration and survival. The encoded receptor is important in development of the nervous system, and the development of organs and tissues derived from the neural crest. This proto-oncogene can undergo oncogenic activation through both cytogenetic rearrangement and activating point mutations. Mutations in this gene are associated with Hirschsprung disease and central hypoventilation syndrome and have been identified in patients with renal agenesis. [provided by RefSeq, Sep 2017] - Molekulargewicht
- 92.29 kDa
- UniProt
- P07949
- Pathways
- RTK Signalweg, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
-