MME Protein (Fc Tag)
Kurzübersicht für MME Protein (Fc Tag) (ABIN6964096)
Target
Alle MME Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Aufreinigungstag / Konjugat
- Dieses MME Protein ist gelabelt mit Fc Tag.
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Verwendungszweck
- Recombinant Human CD10 protein with N-terminal human Fc
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Spezifität
- HFc (Glu99-Ala330) CD10 (Tyr52-Trp750)
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Produktmerkmale
- Extracellular Domain Protein
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Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Haltbarkeit
- 12 months
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- MME (Membrane Metallo-Endopeptidase (MME))
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Andere Bezeichnung
- CD10
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Hintergrund
- The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.
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Molekulargewicht
- predicted molecular mass of 106.1 kDa after removal of the signal peptide.
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Gen-ID
- 4311
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UniProt
- P08473
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Pathways
- RTK Signalweg, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
Target
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