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MME Protein (Fc Tag)

Dieses Recombinant MME-Protein wird in HEK-293 Cells exprimiert.
Produktnummer ABIN6964096

Kurzübersicht für MME Protein (Fc Tag) (ABIN6964096)

Target

Alle MME Proteine anzeigen
MME (Membrane Metallo-Endopeptidase (MME))

Protein-Typ

Recombinant

Spezies

  • 18
  • 5
  • 4
  • 1
Human

Quelle

  • 10
  • 8
  • 2
  • 2
  • 2
  • 2
HEK-293 Cells

Reinheit

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • Aufreinigungstag / Konjugat

    Dieses MME Protein ist gelabelt mit Fc Tag.

    Verwendungszweck

    Recombinant Human CD10 protein with N-terminal human Fc

    Spezifität

    HFc (Glu99-Ala330) CD10 (Tyr52-Trp750)

    Produktmerkmale

    Extracellular Domain Protein

    Aufreinigung

    Purified from cell culture supernatant by affinity chromatography
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Haltbarkeit

    12 months
  • Target

    MME (Membrane Metallo-Endopeptidase (MME))

    Andere Bezeichnung

    CD10

    Hintergrund

    The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.

    Molekulargewicht

    predicted molecular mass of 106.1 kDa after removal of the signal peptide.

    Gen-ID

    4311

    UniProt

    P08473

    Pathways

    RTK Signalweg, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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