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Growth Hormone Receptor Protein (GHR) (AA 19-264) (Fc Tag)

GHR Spezies: Rhesusaffen Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Produktnummer ABIN6809923
$415.38
Zzgl. Versandkosten $45.00
Lieferung in 5 Werktagen
  • Target Alle Growth Hormone Receptor (GHR) Proteine anzeigen
    Growth Hormone Receptor (GHR)
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 19-264
    Spezies
    • 15
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Rhesusaffen
    Quelle
    • 13
    • 9
    • 8
    • 6
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Growth Hormone Receptor Protein ist gelabelt mit Fc Tag.
    Sequenz
    AA 19-264
    Reinheit
    >90 % as determined by SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
  • Target
    Growth Hormone Receptor (GHR)
    Andere Bezeichnung
    Growth Hormone R (GHR Produkte)
    Synonyme
    GHBP, AA986417, GHR/BP, GHR, ghr, ghr.a, zgc:162141, growth hormone receptor, growth hormone receptor L homeolog, growth hormone receptor a, GHR, Ghr, ghr.L, ghr, ghra
    Hintergrund
    Growth hormone receptor (GHR) is also known as somatotropin receptor, growth hormone-binding protein (GHBR), which belongs to the type I cytokine receptor family or Type 1 subfamily. GHR contains one fibronectin type-III domain. GHR / GHBR is expressed in various tissues with high expression in liver and skeletal muscle. The soluble form (GHBP) is produced by phorbol ester-promoted proteolytic cleavage at the cell surface (shedding) by ADAM17/TACE. GHR is receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
    Molekulargewicht
    54.7 kDa
    NCBI Accession
    NP_001036132
    Pathways
    NF-kappaB Signalweg, JAK-STAT Signalweg, Response to Growth Hormone Stimulus
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