IL-13 Protein

Produktnummer ABIN6700025

Hersteller Produkt- Nr.: 009-001-v52-0100

Dieses Recombinant IL-13-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für IL-13 Protein (ABIN6700025)

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: 95,00%

Produktdetails

Hersteller Produkt- Nr.: 009-001-v52-0100

Hersteller: Rockland

Verwendungszweck: Human Interleukin-13 Recombinant Protein

Aufreinigung: Interleukin-13 purity was determined to be greater than 95% as determined by analysis by reducing and non-reducing SDS-pAGE.

Endotoxin-Niveau: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: The activity is determined by the dose dependent proliferation of TF-1 cells and is typically less than 1 ng/mL.

Anwendungsinformationen

Applikationshinweise:

Application Note: Interleukin-13 Recombinant Protein is suitable as a control for polyclonal or monoclonal anti-Interleukin-13 in immunological assays.

Other: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 100 μL

Konzentration: 0.1 mg/mL

Buffer:

Buffer: 0.01 M Sodium Citrate, pH 3.0

Stabilizer: None

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Haltbarkeit: 6 months

Antigendetails

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Andere Bezeichnung: IL13

Hintergrund:

Synonyms: NC30

Background: Interleukin-13 (IL-13) is an important cytokine secreted from Th2 cells. The functions attributed to IL-13 overlap significantly with those of IL-4 (induces IgE secretion from B cells and inhibits expression of inflammatory cytokines such as IL-1β, TNF-α, IL-8 and IL-6), but differs from IL-4 in that IL-13 seems to link inflammatory responses of immune cells to the pathophysiological changes in the surrounding non-immune cells. The receptor subunits of IL-13 consist of IL-4Rα, IL-13Rα1 and IL-13Rα2. Human and mouse IL-13 are cross-reactive. Recombinant human IL-13 is a non-glycosylated variant of native IL-13, containing 115 amino acids (additional Gln at position 113), with a molecular weight of 12.6 kDa.

UniProt: P35225

Pathways: JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport