Survivin Protein (AA 1-142) (Calmodulin (CaM))

Produktnummer ABIN667066

Recombinant Survivin-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für Survivin Protein (AA 1-142) (Calmodulin (CaM)) (ABIN667066)

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 %

Produktdetails

Proteineigenschaft: AA 1-142

Aufreinigungstag / Konjugat: Dieses Survivin Protein ist gelabelt mit Calmodulin (CaM).

Sequenz: MGAPTLPP AWQPFLKDHR ISTFKNWPFL EGCACTPERM AEAGFIHCPT ENEPDLAQCF FCFKELEGWE PDDDPIEEHK KHSSGCAFLS VKKQFEELTL GEFLKLDRER AKNKIAKETN NKKKEFEETA KKVRRAIEQL AAMD

Produktmerkmale: Survivin, AA 1-142, Human, CaM-tagged, Recombinant, E. coli

Aufreinigung: > 90% by SDS-PAGE

Endotoxin-Niveau: < 1 EU per 1ug of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 7.5) containing 0.1M NaCl

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Andere Bezeichnung: Survivin

Hintergrund: Survivin is a human gene that is part of the inhibitor of apoptosis family (IAP). The Survivin protein functions to inhibit caspase activation therefore leading to negative regulation of apoptosis or programmed cell death. Recombinant human Survivin fused to CaM-tag at N-terminus was expressed in E. coli and purified by conventional chromatography techniques.

Molekulargewicht: 33 kDa (294aa) confirmed by MALDI-TOF

Pathways: Apoptose, Zellzyklus, Nuclear Hormone Receptor Binding