SKP1 Protein (AA 1-160)

Produktnummer ABIN666914

Dieses Recombinant SKP1-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für SKP1 Protein (AA 1-160) (ABIN666914)

Target: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 %

Produktdetails

Proteineigenschaft: AA 1-160

Sequenz: MPSIKLQSSD GEIFEVDVEI AKQSVTIKTM LEDLGMDDEG DDDPVPLPNV NAAILKKVIQ WCTHHKDDPP PPEDDENKEK RTDDIPVWDQ EFLKVDQGTL FELILAANYL DIKGLLDVTC KTVANMIKGK TPEEIRKTFN IKNDFTEEEE AQVGSTQFCL

Produktmerkmale: SKP1, 1- 160aa, Human, E.coli

Aufreinigung: > 90% by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 50 mM NaCl, 10 % glycerol

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Andere Bezeichnung: SKP1

Hintergrund: S-phase kinase-associated protein 1, also known as SKP1, is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to proteins containing an F-box motif, such as cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin dependent proteolysis. It is also involved in the control of beta-catenin levels and the activity of beta-catenin dependent TCF transcription factors. Recombinant human SKP1 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Molekulargewicht: 18 kDa (160aa) confirmed by MALDI-TOF

NCBI Accession: NP_008861

Pathways: Zellzyklus, Hedgehog Signalweg, Mitotic G1-G1/S Phases