SKP1 Protein (AA 1-160)

Produktnummer ABIN666914

Produktdetails

Target: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-160

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Produktmerkmale: SKP1, 1- 160aa, Human, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 50mM NaCl, 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Andere Bezeichnung: SKP1 (SKP1 Produkte)

Synonyme: EMC19 Protein, OCP-II Protein, OCP2 Protein, SKP1A Protein, TCEB1L Protein, p19A Protein, 15kDa Protein, 2610043E24Rik Protein, 2610206H23Rik Protein, SKP1 Protein, Tceb1l Protein, p19Skp1 Protein, Skp1a Protein, skp1a Protein, zgc:73186 Protein, ocp2 Protein, emc19 Protein, ocp-ii Protein, tceb1l Protein, ARABIDOPSIS SKP1 HOMOLOGUE 1 Protein, ASK1 Protein, ATSKP1 Protein, S phase kinase-associated protein 1 Protein, T4O12.17 Protein, T4O12_17 Protein, UFO INTERACTING PROTEIN 1 Protein, UIP1 Protein, ocp-2 Protein, S-phase kinase associated protein 1 Protein, S-phase kinase-associated protein 1 Protein, S-phase kinase-associated protein 1 pseudogene Protein, S-phase kinase-associated protein 1A Protein, S-phase kinase-associated protein 1 S homeolog Protein, S phase kinase-associated protein 1 Protein, SKP1 Protein, skp1 Protein, LOC100340043 Protein, Skp1a Protein, Skp1 Protein, skp1.S Protein

Hintergrund: S-phase kinase-associated protein 1, also known as SKP1, is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to proteins containing an F-box motif, such as cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin dependent proteolysis. It is also involved in the control of beta-catenin levels and the activity of beta-catenin dependent TCF transcription factors. Recombinant human SKP1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: EMC19, MGC34403, OCP-II, OCP2, p19A, SKP1A, TCEB1L, S-phase kinase-associated protein 1 isoform a Cyclin A/CDK2 associated p19, Cyclin A/CDK2 associated protein p19, MGC34403, OCP 2, OCP II, OCP II protein, OCPII, Organ of Corti protein 2, p19skp1, RNA polymerase II elongation factor like protein, RNA polymerase II elongation factor like protein OCP2, S phase kinase associated protein 1, S phase kinase associated protein 1A, S phase kinase associated protein 1A p19A, SIII, Skp 1, SKP 1A, Transcription elongation factor B, Transcription Elongation Factor B 1 like, Transcription elongation factor B SIII polypeptide 1 like. NCBI no.: NP_008861

Molekulargewicht: 18 kDa (160aa), confirmed by MALDI-TOF.

Pathways: Zellzyklus, Hedgehog Signalweg, Mitotic G1-G1/S Phases