Prolactin Protein (PRL) (AA 30-228)
Kurzübersicht für Prolactin Protein (PRL) (AA 30-228) (ABIN5777732)
Target
Alle Prolactin (PRL) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- AA 30-228
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Sequenz
- MQPLPICSAG DCQTSLRELF DRVVILSHYI HTLYTDMFIE FDKQYVQDRE FMVKVINDCP TSSLATPEDK EQALKVPPEV LLNLILSLVQ SSSDPLFQLI TGVGGIQEAP EYILSRAKEI EEQNKQLLEG VEKIISQAYP EAKGNGIYFV WSQLPSLQGV DEESKILSLR NTIRCLRRDS HKVDNFLKVL RCQIAHQNNC
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Endotoxin-Niveau
- < 1.0 EU per 1ug of protein (determined by LAL method)
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Biological Activity Comment
- Measured in a cell proliferation assay using Nb2-11 Rat lymphoma cells. The ED50 for this effect is less or equal 3 ng/ml.
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Prolactin (PRL) (Active) protein
PRL Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Prolactin (PRL) protein (His tag)PRL Spezies: Schaf Wirt: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Prolactin (PRL) protein (His tag)PRL Spezies: Maus Wirt: Baculovirus infected Insect Cells Recombinant > 92 % as determined by SDS-PAGE
Prolactin (PRL) (AA 29-227) protein (GST tag)PRL Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Prolactin (PRL) (AA 29-227) protein (Fc Tag)PRL Spezies: Human Wirt: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Prolactin (PRL) (AA 29-227) protein (Fc Tag,AVI tag,Biotin)PRL Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Bioactivity Validated
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid. In Phosphate buffered saline ( pH 7.4)
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Prolactin (PRL)
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Andere Bezeichnung
- Prolactin
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Hintergrund
- Prolactin, also known as prl, is a hormone synthesized and secreted by lactotrope cells in the adenohypophysis (anterior pituitary gland). Prolactin has many effects, the most significant of which is to stimulate the mammary glands to produce milk (lactation). Increased serum prolactin during pregnancy causes enlargement of the mammary glands of the breasts and increases the production of milk. Recently, prolactin has demonstrated broader roles in breast cancer development, regulation of reproductive function, and immuno-regulation. Recombinant mouse Prolactin, was expressed in E.coli and purified by using conventional chromatography techniques.
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Molekulargewicht
- 22.7kDa (200aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_035294
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UniProt
- Q9CPQ2
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Pathways
- JAK-STAT Signalweg, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Protein targeting to Nucleus
Target
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