TNFRSF11A Protein (AA 30-212) (Fc Tag)
Kurzübersicht für TNFRSF11A Protein (AA 30-212) (Fc Tag) (ABIN6253593)
Target
Alle TNFRSF11A Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 30-212
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Aufreinigungstag / Konjugat
- Dieses TNFRSF11A Protein ist gelabelt mit Fc Tag.
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Sequenz
- AA 30-212
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Endotoxin-Niveau
- Less than 0.1 EU per μg by the LAL method.
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Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 30-212) protein (Fc Tag)
TNFRSF11A Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 31-214) protein (Fc Tag)TNFRSF11A Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 30-212) protein (His-DYKDDDDK-Strep II Tag)TNFRSF11A Spezies: Human Wirt: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) protein (His tag)TNFRSF11A Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 28-202) protein (His tag)TNFRSF11A Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) protein (Fc Tag)TNFRSF11A Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) protein (His tag)TNFRSF11A Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 28-212) protein (hIgG-His-tag)TNFRSF11A Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 31-130) protein (GST tag)TNFRSF11A Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
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Handhabung
- Please avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
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Andere Bezeichnung
- RANK
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Hintergrund
- RANK / TNFRSF11A is a member of the tumor necrosis factor receptor family. RANK / TNFRSF11A shares significant amino acid homology with other members of the TNF R family in its extracellular four cysteine-rich repeats. Functional genomics in mice showed that RANKL (TNFSF11), a member of the TNF ligand superfamily, and RANK (TNFRSF11a), the cognate TNFR family receptor for RANKL, were essential for osteoclastogenesis in vivo. A functional interaction between RANKL, expressed by bone stromal cells of the osteoblast lineage, and RANK, expressed by osteoclast precursors of hematopoietic myeloid lineage, is necessary for osteoclast differentiation, survival, and activation.
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Molekulargewicht
- 47.2 kDa
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NCBI Accession
- NP_003830
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Pathways
- NF-kappaB Signalweg
Target
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