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BTLA Protein (AA 31-157) (His tag)

BTLA Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN7281321
  • Target Alle BTLA Proteine anzeigen
    BTLA (B and T Lymphocyte Associated (BTLA))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 31-157
    Spezies
    • 26
    • 9
    • 2
    • 1
    Human
    Quelle
    • 28
    • 3
    • 3
    • 3
    • 1
    Baculovirus infected Insect Cells
    Aufreinigungstag / Konjugat
    Dieses BTLA Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    ADPKESCDVQ LYIKRQSEHS ILAGDPFELE CPVKYCANRP HVTWCKLNGT TCVKLEDRQT SWKEEKNISF FILHFEPVLP NDNGSYRCSA NFQSNLIESH STTLYVTDVK SASERPSKDE MASRPWLLYS HHHHHH
    Reinheit
    > 90 % by SDS - PAGE
    Endotoxin-Niveau
    < 1.0 EU per 1ug of protein (determined by LAL method)
    Top Product
    Discover our top product BTLA Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    BTLA (B and T Lymphocyte Associated (BTLA))
    Andere Bezeichnung
    BTLA (BTLA Produkte)
    Hintergrund
    BTLA, also known as B- and T-lymphocyte attenuator isoform 1, is an inhibitory molecule which belongs to the Ig superfamily. It is a type 1 transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. This protein is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1(PD-1). Also, it is a ligand for tumor necrosis factor (receptor) superfamily, member 14 (TNFRSF14), also known as herpes virus entry mediator (HVEM). BTLA-HVEM complexes negatively regulate T-cell immune responses. Recombinant human BTLA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molekulargewicht
    15.7kDa (136aa) 18-28kDa (SDS-PAGE under reducing conditions)
    NCBI Accession
    NP_861445
    UniProt
    Q7Z6A9
    Pathways
    Cancer Immune Checkpoints
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