Kallikrein 7 Protein (KLK7) (AA 28-253) (His tag)

Produktnummer ABIN5713584

Dieses Recombinant Kallikrein 7-Protein wird in Hefe exprimiert.

Kurzübersicht für Kallikrein 7 Protein (KLK7) (AA 28-253) (His tag) (ABIN5713584)

Target: Kallikrein 7 (KLK7)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Hefe

Applikation: SDS-PAGE (SDS)

Reinheit: Greater than 90 % as determined by SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 28-253

Aufreinigungstag / Konjugat: Dieses Kallikrein 7 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Kallikrein-7(KLK7)

Sequenz: DKIIDGAPCA RGSHPWQVAL LSGNQLHCGG VLVNERWVLT AAHCKMNEYT VHLGSDTLGD RRAQRIKASK SFRHPGYSTQ THVNDLMLVK LNSQARLSSM VKKVRLPSRC EPPGTTCTVS GWGTTTSPDV TFPSDLMCVD VKLISPQDCT KVYKDLLENS MLCAGIPDSK KNACNGDSGG PLVCRGTLQG LVSWGTFPCG QPNDPGVYTQ VCKFTKWIND TMKKHR

Produktmerkmale: N-terminal 6xHis-tagged

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: Tris-based buffer50 % glycerol

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Haltbarkeit: 6-12 months

Antigendetails

Target: Kallikrein 7 (KLK7)

Andere Bezeichnung: KLK7

Hintergrund: May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.

Molekulargewicht: 26.7 kDa

Gen-ID: 5650

UniProt: P49862

Pathways: Komplementsystem