Kallikrein 7 Protein (KLK7) (AA 28-253)

Produktnummer ABIN5713584

Dieses Recombinant Kallikrein 7-Protein wird in Hefe exprimiert.

Kurzübersicht für Kallikrein 7 Protein (KLK7) (AA 28-253) (ABIN5713584)

Target: Kallikrein 7 (KLK7)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Hefe

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 %

Produktdetails

Proteineigenschaft: AA 28-253

Sequenz: HHSSGLVPRG SHMDDDDKII DGAPCARGSH PWQVALLSGN QLHCGGVLVN ERWVLTAAHC KMNEYTVHLG SDTLGDRRAQ RIKASKSFRH PGYSTQTHVN DLMLVKLNSQ ARLSSMVKKV RLPSRCEPPG TTCTVSGWGT TTSPDVTFPS DLMCVDVKLI SPQDCTKVYK DLLENSMLCA GIPDSKKNAC NGDSGGPLVC RGTLQGLVSW GTFPCGQPND PGVYTQVCKF TKWINDTMKK HR

Aufreinigung: SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: Kallikrein 7 (KLK7)

Andere Bezeichnung: KLK7

Hintergrund: May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.

Molekulargewicht: 26.4 kDa

UniProt: P49862

Pathways: Komplementsystem