GRK2 Protein (AA 2-634, partial) (His tag)
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- Target Alle GRK2 (ADRBK1) Proteine anzeigen
- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- partial, AA 2-634
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses GRK2 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- ADLEAVLADV SYLMAMEKSK ATPAARASKK ILLPEPSIRS VMQKYLEDRG EVTFEKIFSQ KLGYLLFRDF CLNHLEEARP LVEFYEEIKK YEKLETEEER VARSREIFDS YIMKELLACS HPFSKSATEH VQGHLGKKQV PPDLFQPYIE EICQNLRGDV FQKFIESDKF TRFCQWKNVE LNIHLTMNDF SVHRIIGRGG FGEVYGCRKA DTGKMYAMKC
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
- Top Product
- Discover our top product ADRBK1 Protein
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Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 1-689) (Active) protein (GST tag)
ADRBK1 Spezies: Human Wirt: Insect cells (Sf21) Recombinant SDS, Func Active
Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 1-689) protein (GST tag)ADRBK1 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AA, AP
Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 1-689) protein (Strep Tag)Crystallography grade ADRBK1 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 1-689) protein (Strep Tag)Crystallography grade ADRBK1 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) protein (Myc-DYKDDDDK Tag)ADRBK1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
- Andere Bezeichnung
- ARBK1 (ADRBK1 Produkte)
- Synonyme
- Adrbk-1 Protein, Bark-1 Protein, GRK2 Protein, betaARK1 Protein, BARK1 Protein, BETA-ARK1 Protein, GRK-2 Protein, Grk2 Protein, beta-adrenergic receptor kinase 1 Protein, G protein-coupled receptor kinase 2 Protein, Tsp_00497 Protein, grk2 Protein, Grk2 Protein, GRK2 Protein
- Hintergrund
- Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of th. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
- Molekulargewicht
- 29.7 kDa
- UniProt
- P25098
- Pathways
- EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
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