GRK2 Protein (Myc-DYKDDDDK Tag)
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- Target Alle GRK2 (ADRBK1) Proteine anzeigen
- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses GRK2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human Beta-ARK-1 / ADRBK1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ADRBK1 Protein
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Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 1-689) (Active) protein (GST tag)
ADRBK1 Spezies: Human Wirt: Insect cells (Sf21) Recombinant SDS, Func Active
Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 1-689) protein (GST tag)ADRBK1 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AA, AP
Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 1-689) protein (Strep Tag)Crystallography grade ADRBK1 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 1-689) protein (Strep Tag)Crystallography grade ADRBK1 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 2-634), (partial) protein (His tag)ADRBK1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
- Andere Bezeichnung
- beta-Ark-1,adrbk1 (ADRBK1 Produkte)
- Synonyme
- Adrbk-1 Protein, Bark-1 Protein, GRK2 Protein, betaARK1 Protein, BARK1 Protein, BETA-ARK1 Protein, GRK-2 Protein, Grk2 Protein, beta-adrenergic receptor kinase 1 Protein, G protein-coupled receptor kinase 2 Protein, Tsp_00497 Protein, grk2 Protein, Grk2 Protein, GRK2 Protein
- Hintergrund
- The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
- Molekulargewicht
- 79.4 kDa
- NCBI Accession
- NP_001610
- Pathways
- EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
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