ACVA Protein
Kurzübersicht für ACVA Protein (ABIN5676019)
Target
Alle ACVA Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS
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Produktmerkmale
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Purified recombinant Human Activin A protein
Expression System: Hi-5 cells
Bioactivity: The ED50 as determined by its ability to inhibit the proliferation of Mouse MPC-11 cells is ? 2 ng/mL, corresponding to a specific activity of ? 5 x 10^5 units/mg. -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Kommentare
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Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute in water to a concentration of 0.5 mg/mL. Do not vortex.
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Buffer
- Lyophilized from 10 mM Citric Acid pH 3.0.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- ACVA (Activin A (ACVA))
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Andere Bezeichnung
- Activin A
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Hintergrund
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Activin A is a TGF beta family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF beta antagonist, Follistatin.
Alternative Names: Activin beta-A protein, Inhibin beta-A protein -
Molekulargewicht
- 26 kDa
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Pathways
- Hormone Transport, Peptide Hormone Metabolism
Target
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