CCL3 Protein

Produktnummer ABIN2830201

Recombinant CCL3-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für CCL3 Protein (ABIN2830201)

Target: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Ratte

Quelle: Escherichia coli (E. coli)

Applikation: Functional Studies (Func)

Reinheit: >98 % as determined by SDS-PAGE and HPLC.

Produktdetails

Sequenz: APYGADTPTA CCFSYGRQIP RKFIADYFET SSLCSQPGVI FLTKRNRQIC ADPKETWVQE YITELELNA

Produktmerkmale: Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemoattract bioassay using human blood monocytes is in a concentration range of 10-100 ng/mL.

Sterilität: 0.2 μm filtered

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Antigendetails

Target: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Andere Bezeichnung: Ccl3

Hintergrund: Relevance: Monokine with inflammatory and chemokinetic properties. Has chemotactic activity for monocytes, neutrophils, eosinophils, basophils, and lymphocytes. Required for lung TNF-alpha production, neutrophil recruitment and subsequent lung injury and may function as an autocrine mediator for the macrophage production of TNF-alpha which in turn up-regulates vascular adhesion molecules required for neutrophil influx. This protein binds heparin.
Synonyms: Macrophage inflammatory protein 1-alpha, Small-inducible cytokine A3

Molekulargewicht: 7.9 kDa

UniProt: P50229

Pathways: Cellular Response to Molecule of Bacterial Origin, Autophagie