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PLGF Protein

PGF Spezies: Human Wirt: Insect cells (Sf9) Recombinant >95 % (SDS-PAGE) SDS Active
Produktnummer ABIN2745802
  • Target Alle PLGF (PGF) Proteine anzeigen
    PLGF (PGF) (Placenta Growth Factor (PGF))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 18
    • 8
    • 4
    • 3
    • 1
    Human
    Quelle
    • 14
    • 11
    • 4
    • 2
    • 2
    • 1
    Insect cells (Sf9)
    Applikation
    SDS-PAGE (SDS)
    Verwendungszweck
    PLGF (human) (rec.)
    Kreuzreaktivität
    Human
    Produktmerkmale
    Human PLGF (131aa).
    Reinheit
    >95 % (SDS-PAGE)
    Biological Activity Comment
    Measured by its ability to bind to immobilized rhsFlt-1 in a functional ELISA. Recombinant human PLGF can bind to immobilized rhsFlt-1 (100ng/well) with a linear range at 0.5-10ng/ml.
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    Discover our top product PGF Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with 50 mM acetic acid or PBS/water. This solution can be diluted into other buffered solutions or stored frozen for future use.
    Handhabung
    After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung

    Short Term Storage: +4°C

    Long Term Storage: -20°C

    Use & Stability: Stable for at least 6 months after receipt when stored at -20°C.

    Haltbarkeit
    6 months
  • Target
    PLGF (PGF) (Placenta Growth Factor (PGF))
    Andere Bezeichnung
    PLGF (PGF Produkte)
    Hintergrund

    Placenta Growth Factor, PLGF-1, PLGF-131

    Human placenta growth factor-1 (PLGF-1, PLGF) binds to the receptor FLT1/VEGFR-1. It acts as a potent chemoattractant for monocytes and only as a very weak mitogen for some endothelial cell types. The physiological function in vivo is still controversial. In several reports it was shown not to be a potent mitogen for endothelial cells and not angiogenic in vivo by using different assays. It was shown that PLGF from cell culture supernatants was angiogenic in the CAM assay and in the rabbit cornea assay.

    Molekulargewicht
    ~34kDa (dimer)
    UniProt
    P49763
    Pathways
    VEGFR1 Specific Signals
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