PLGF Protein

Produktnummer ABIN2745802

Dieses Recombinant PLGF-Protein wird in Insect cells (Sf9) exprimiert.

Kurzübersicht für PLGF Protein (ABIN2745802)

Target: PLGF (PGF) (Placenta Growth Factor (PGF))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Insect cells (Sf9)

Applikation: SDS-PAGE (SDS)

Reinheit: >95 % (SDS-PAGE)

Produktdetails

Verwendungszweck: PLGF (human) (rec.)

Kreuzreaktivität: Human

Produktmerkmale: Human PLGF (131aa).

Biological Activity Comment: Measured by its ability to bind to immobilized rhsFlt-1 in a functional ELISA. Recombinant human PLGF can bind to immobilized rhsFlt-1 (100ng/well) with a linear range at 0.5-10ng/ml.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with 50 mM acetic acid or PBS/water. This solution can be diluted into other buffered solutions or stored frozen for future use.

Handhabung: After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

Short Term Storage: +4°C

Long Term Storage: -20°C

Use & Stability: Stable for at least 6 months after receipt when stored at -20°C.

Haltbarkeit: 6 months

Antigendetails

Target: PLGF (PGF) (Placenta Growth Factor (PGF))

Andere Bezeichnung: PLGF

Hintergrund:

Placenta Growth Factor, PLGF-1, PLGF-131

Human placenta growth factor-1 (PLGF-1, PLGF) binds to the receptor FLT1/VEGFR-1. It acts as a potent chemoattractant for monocytes and only as a very weak mitogen for some endothelial cell types. The physiological function in vivo is still controversial. In several reports it was shown not to be a potent mitogen for endothelial cells and not angiogenic in vivo by using different assays. It was shown that PLGF from cell culture supernatants was angiogenic in the CAM assay and in the rabbit cornea assay.

Molekulargewicht: ~34kDa (dimer)

UniProt: P49763

Pathways: VEGFR1 Specific Signals