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Placenta Growth Factor (PGF) (AA 19-170) (Active) protein (His tag) Protein

PGF Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN2181647
$319.00
Zzgl. Versandkosten $45.00
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  • Target Alle PLGF (PGF) Proteine anzeigen
    PLGF (PGF)
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 19-170
    Spezies
    • 19
    • 8
    • 4
    • 3
    • 1
    Human
    Quelle
    • 14
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses PLGF Protein ist gelabelt mit His tag.
    Sequenz
    AA 19-170
    Produktmerkmale
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 20.2 kDa. The protein migrates as 28-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    100 mM Acetic Acid, pH 3.0
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • Target
    PLGF (PGF)
    Andere Bezeichnung
    PLGF (PGF Produkte)
    Synonyme
    D12S1900, PGFL, PLGF, PlGF-2, SHGC-10760, AI854365, PIGF, Plgf, PlGF, placental growth factor, placenta growth factor, PGF, Pgf, PLGF
    Hintergrund
    Placental growth factor (PGF) is also known as vascular endothelial growth factor-related protein, PLGF and PlGF2, is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. PGF is actived in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. PlGF2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
    Molekulargewicht
    18.2 kDa
    NCBI Accession
    NP_002623
    Pathways
    VEGFR1 Specific Signals
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