FZD5 Protein (Frizzled Family Receptor 5) (AA 27-180) (Fc Tag)
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- Target Alle FZD5 Proteine anzeigen
- FZD5 (Frizzled Family Receptor 5 (FZD5))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 27-180
- Spezies
- Human, Maus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses FZD5 Protein ist gelabelt mit Fc Tag.
- Applikation
- SDS-PAGE (SDS)
- Spezifität
- Binds to human and mouse Wnt3a.
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
- The cysteine-rich domain (CRD) of human Frizzled-5 (aa 27-180) is fused at the C-terminus to the Fc portion of human IgG1.
- Reinheit
- >95 % (SDS-PAGE)
- Endotoxin-Niveau
- <0.01EU/μg purified protein (LAL test, Lonza).
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Frizzled Family Receptor 5 (FZD5) (AA 27-167) protein (Fc Tag)
FZD5 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Frizzled Family Receptor 5 (FZD5) protein (Fc Tag)FZD5 Spezies: Maus Wirt: CHO Cells Recombinant > 95 % as determined by SDS-PAGE
Frizzled Family Receptor 5 (FZD5) (AA 27-585) protein (rho-1D4 tag)Crystallography grade FZD5 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Frizzled Family Receptor 5 (FZD5) (AA 27-238) protein (His tag)Crystallography grade FZD5 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Frizzled Family Receptor 5 (FZD5) (AA 27-238) protein (His tag)Crystallography grade FZD5 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Frizzled Family Receptor 5 (FZD5) (AA 27-585) protein (rho-1D4 tag)Crystallography grade FZD5 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Frizzled Family Receptor 5 (FZD5) (AA 1-585) protein (GST tag)FZD5 Spezies: Human Wirt: Wheat germ Recombinant AA, AP, ELISA, WB
Frizzled Family Receptor 5 (FZD5) (AA 72-161) protein (GST tag)FZD5 Spezies: Human Wirt: Wheat germ Recombinant AA, AP, ELISA, WB
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Inhibits Wnt3a activation in a stoechiometric manner.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with 50 μL sterile water.
- Konzentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Haltbarkeit
- 6 months
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- Target
- FZD5 (Frizzled Family Receptor 5 (FZD5))
- Andere Bezeichnung
- Frizzled-5 (FZD5 Produkte)
- Synonyme
- C2orf31, HFZ5, 5330434N09Rik, AI427138, Fz-5, Fz5, mFz5, Xfz5, frizzled5, frizzled5a, fz5, fzd5-A, fz2, fz8c, fzd8c, zg02, frizzled class receptor 5, frizzled class receptor 5 S homeolog, FZD5, Fzd5, fzd5.S, fzd5
- Hintergrund
- Wnts are lipid-modified morphogens that control many processes during development, stem cell maintenance and homeostasis and their aberrant regulation has been linked to diseases in man including diabetes, neurodegeneration and cancer. Three distinct receptor families mediate Wnt signaling: Fzs, the single-pass LRP5/6 co-receptors and the atypical tyrosine kinase receptors Ror2 and Ryk. Frizzled proteins can activate canonical Wnt/beta-catenin signaling as well as non-canonical pathways (Wnt/Ca2+ pathways and planar cell polarity). The cysteine-rich domain (CRD) of the frizzled receptors situated on the extracellular part of the receptor is sufficient to bind the Wnt ligands.
- Molekulargewicht
- ~50kDa (SDS-PAGE)
- UniProt
- Q13467
- Pathways
- WNT Signalweg
