ULBP2 Protein

Produktnummer ABIN2735004

Dieses Recombinant ULBP2-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für ULBP2 Protein (ABIN2735004)

Target: ULBP2 (UL16 Binding Protein 2 (ULBP2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Applikation: Antibody Production (AbP), Standard (STD)

Reinheit: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Produktdetails

Produktmerkmale:

• Recombinant human ULBP2 / NKG2D ligand 2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Endotoxin-Niveau: < 0.1 EU per μg protein as determined by LAL test

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ULBP2 (UL16 Binding Protein 2 (ULBP2))

Andere Bezeichnung: Ulbp2,nkg2d Ligand 2

Hintergrund: This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6.

Molekulargewicht: 22.8 kDa

NCBI Accession: NP_079493