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PAK1 Protein (Transcript Variant 1)

PAK1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, STD, PI Active
Produktnummer ABIN2728167
  • Target Alle PAK1 Proteine anzeigen
    PAK1 (P21-Activated Kinase 1 (PAK1))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    Transcript Variant 1
    Spezies
    • 10
    • 1
    • 1
    Human
    Quelle
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Applikation
    Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
    Spezifität
    Optimal preservation of protein structure, post-translational modifications and functions.
    Produktmerkmale
    • Recombinant human PAK1 (transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Reinheit
    > 90 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin-Niveau
    <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Specific activity was determined as 32,638 pmoles/min/μg, according to the Zlyte assay protocol
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol, 5 mM DTT.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PAK1 (P21-Activated Kinase 1 (PAK1))
    Andere Bezeichnung
    Pak1 (PAK1 Produkte)
    Synonyme
    X-PAK1 Protein, XPak1 Protein, pak Protein, pak-1 Protein, pakalpha Protein, PAKalpha Protein, AW045634 Protein, PAK-1 Protein, Paka Protein, p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog Protein, p21 (RAC1) activated kinase 1 Protein, p21 protein (Cdc42/Rac)-activated kinase 1 Protein, Serine/threonine-protein kinase pak-1 Protein, pak1.S Protein, PAK1 Protein, Pak1 Protein, pak-1 Protein
    Hintergrund
    This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht
    33.6 kDa
    NCBI Accession
    NP_001122092
    Pathways
    MAPK Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
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