MAPK7 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2725433

Produktdetails

Target: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 3

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MAPK7 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human MAPK7 / ERK5 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Andere Bezeichnung: Mapk7,erk5 (MAPK7 Produkte)

Synonyme: BMK1 Protein, ERK4 Protein, ERK5 Protein, PRKM7 Protein, Erk5-T Protein, ATMPK7 Protein, F8D23.5 Protein, F8D23_5 Protein, MAP kinase 7 Protein, Bmk1 Protein, Erk5 Protein, Prkm7 Protein, ERK-5 Protein, bmk1 Protein, erk4 Protein, mapk7 Protein, prkm7 Protein, mitogen-activated protein kinase 7 Protein, MAP kinase 7 Protein, mitogen-activated protein kinase 7 L homeolog Protein, MAPK7 Protein, Mapk7 Protein, MPK7 Protein, mapk7.L Protein

Hintergrund: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

Molekulargewicht: 88.2 kDa

NCBI Accession: NP_002740

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling