LIN28A Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2724751

Produktdetails

Target: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses LIN28A Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human LIN28 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Andere Bezeichnung: Lin28 (LIN28A Produkte)

Synonyme: CSDD1 Protein, LIN-28 Protein, LIN28 Protein, ZCCHC1 Protein, lin-28A Protein, AL024421 Protein, ENSMUSG00000070700 Protein, Gm10299 Protein, Lin-28 Protein, Lin28 Protein, Tex17 Protein, csdd1 Protein, lin-28 Protein, lin28 Protein, zcchc1 Protein, sb:cb650 Protein, zgc:55584 Protein, RGD1566408 Protein, lin-28 homolog A Protein, lin-28 homolog A (C. elegans) Protein, lin-28 homolog A S homeolog Protein, LIN28A Protein, Lin28a Protein, lin28a.S Protein, lin28a Protein

Hintergrund: This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.

Molekulargewicht: 22.6 kDa

NCBI Accession: NP_078950

Pathways: Stem Cell Maintenance