Hexokinase 2 Protein (HK2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2722680

Dieses Recombinant Hexokinase 2-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für Hexokinase 2 Protein (HK2) (Myc-DYKDDDDK Tag) (ABIN2722680)

Target: Hexokinase 2 (HK2)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Applikation: Antibody Production (AbP), Standard (STD)

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Produktdetails

Aufreinigungstag / Konjugat: Dieses Hexokinase 2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Produktmerkmale:

• Recombinant human Hexokinase-2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Hexokinase 2 (HK2)

Andere Bezeichnung: Hexokinase-2

Hintergrund: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Molekulargewicht: 102.2 kDa

NCBI Accession: NP_000180

Pathways: PI3K-Akt Signalweg, Carbohydrate Homeostasis, Warburg Effekt