Osteoactivin Protein (GPNMB) (Transcript Variant 1)

Produktnummer ABIN2722180

Dieses Recombinant Osteoactivin-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für Osteoactivin Protein (GPNMB) (Transcript Variant 1) (ABIN2722180)

Target: Osteoactivin (GPNMB)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Applikation: Antibody Production (AbP), Standard (STD)

Reinheit: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Produktdetails

Proteineigenschaft: Transcript Variant 1

Produktmerkmale:

• Recombinant human GPNMB / HGFIN (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Endotoxin-Niveau: < 0.1 EU per μg protein as determined by LAL test

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Osteoactivin (GPNMB)

Andere Bezeichnung: Gpnmb,hgfin

Hintergrund: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 53.1 kDa

NCBI Accession: NP_001005340