Osteoactivin Protein (GPNMB) (His tag)
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- Target Alle Osteoactivin (GPNMB) Proteine anzeigen
- Osteoactivin (GPNMB)
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Osteoactivin Protein ist gelabelt mit His tag.
- Applikation
- Western Blotting (WB)
- Produktmerkmale
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Measured by the ability of the immobilized protein to induce pro-MMP-9 secretion by NHLF human normal lung fibroblasts. The ED50 for this effect is typically 4 - 16 μg/mL.
- Reinheit
- >95 % as determined by SDS-PAGE.
- Top Product
- Discover our top product GPNMB Protein
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Osteoactivin (GPNMB) (AA 23-502) protein (His tag)
GPNMB Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Osteoactivin (GPNMB) (AA 23-486) protein (His tag)GPNMB Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Osteoactivin (GPNMB) (AA 1-572) protein (GST tag)GPNMB Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Osteoactivin (GPNMB) (AA 104-203) protein (GST tag)GPNMB Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Osteoactivin (GPNMB) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)GPNMB Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Applikationshinweise
- This recombinant protein can be used for WB. For research use only.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Lagerung
- -80 °C,-20 °C
- Informationen zur Lagerung
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- Target
- Osteoactivin (GPNMB)
- Andere Bezeichnung
- Osteoactivin (GPNMB Produkte)
- Synonyme
- HGFIN Protein, NMB Protein, DC-HIL Protein, Dchil Protein, ipd Protein, glycoprotein nmb Protein, glycoprotein (transmembrane) nmb Protein, glycoprotein nmb L homeolog Protein, Gpnmb Protein, GPNMB Protein, gpnmb.L Protein
- Hintergrund
- Transmembrane glycoprotein NMB (GPNMB) is also known as Transmembrane glycoprotein HGFIN, DC-HIL and Osteoactivin (OA), which belongs to the PMEL/NMB family. GPNMB contains one PKD domain. GPNMB is a transmembrane glycoprotein that is up-regulated in various cancer cells, including in glioblastoma multiforme and is expressed in many melanoma cells, as well as in tissue macrophages. GPNMB protein acts as a downstream mediator of BMP-2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization, and functions as a negative regulator of inflammation in macrophages.
- Molekulargewicht
- 52.9 kDa
- Gen-ID
- 10457
- UniProt
- Q14956
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