Midkine Protein
Kurzübersicht für Midkine Protein (ABIN2468825)
Target
Alle Midkine (MDK) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- MVAKKKEKVK KGSECSEWTW GPCTPSSKDC GMGFREGTCG AQTQRVHCKV PCNWKKEFGA DCKYKFESWG ACDGSTGTKA RQGTLKKARY NAQCQETIRV TKPCTSKTKS KTKAKKGKGK D
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Produktmerkmale
- Biological activity was determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/mL.
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Endotoxin-Niveau
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Midkine (Neurite Growth-Promoting Factor 2) (MDK) (Active) protein
MDK Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) protein (His-Avi Tag)MDK Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 23-140) protein (His tag)MDK Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-140) protein (His tag)MDK Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 1-143) protein (GST tag)MDK Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) protein (His tag)MDK Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) protein (Fc Tag)MDK Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 23-143) protein (Fc Tag)MDK Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Handhabung
- As with any protein, exposing Midkine recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Midkine stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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Haltbarkeit
- 24 months
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- Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))
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Andere Bezeichnung
- Midkine
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Hintergrund
- Midkine and its functionally-related protein Pleiotrophin are heparin-binding neurotrophic factors that signal through the same receptor, known as anaplastic lymphoma kinase (ALK). MK plays an important regulatory role in epithelial-mesenchymal interactions during fetal development and in postnatal lung development. MK chemoattracts embryonic neurons, neutrophils and macrophages, and by signaling through the ALK receptor it exerts angiogenic, growth and survival activities during tumorgenesis. Recombinant murine Midkine is a 13.4 kDa protein containing 121 amino acid residues including five intra-molecular disulfide bonds.
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Gen-ID
- 17242
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NCBI Accession
- NP_001012335
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OMIM
- 59894790
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UniProt
- P12025
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Pathways
- RTK Signalweg, M Phase, Skeletal Muscle Fiber Development
Target
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