IL-15 Protein
Kurzübersicht für IL-15 Protein (ABIN2468613)
Target
Alle IL-15 (IL15) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- MNWIDVRYDL EKIESLIQFI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VIESGCKECE ELEERNFTEF LQSFIHIVQM FINTS
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Produktmerkmale
- The ED50 was determined by the dose - dependant stimulation of the proliferation of murine CTLL - 2 cells is < 10 ng/mL, corresponding to a specific activity of > 1 x 105 units/mg.
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Endotoxin-Niveau
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Handhabung
- As with any protein, exposing IL-15 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted IL-15 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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Haltbarkeit
- 24 months
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- IL-15 (IL15) (Interleukin 15 (IL15))
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Andere Bezeichnung
- IL-15
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Hintergrund
- IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant rat IL-15 is a 13.5 kDa protein consisting of 115 amino acid residues.
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Gen-ID
- 25670
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NCBI Accession
- NP_037261
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OMIM
- 6981092
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UniProt
- P97604
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Pathways
- JAK-STAT Signalweg, Glycosaminoglycan Metabolic Process
Target
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