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IL-15 Protein

Dieses Recombinant IL-15-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN2468613

Kurzübersicht für IL-15 Protein (ABIN2468613)

Target

Alle IL-15 (IL15) Proteine anzeigen
IL-15 (IL15) (Interleukin 15 (IL15))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 28
  • 9
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Ratte

Quelle

  • 39
  • 10
  • 9
  • 4
  • 1
  • 1
Escherichia coli (E. coli)

Reinheit

< 98 % by SDS-PAGE gel and HPLC analyses.
  • Sequenz

    MNWIDVRYDL EKIESLIQFI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VIESGCKECE ELEERNFTEF LQSFIHIVQM FINTS

    Produktmerkmale

    The ED50 was determined by the dose - dependant stimulation of the proliferation of murine CTLL - 2 cells is < 10 ng/mL, corresponding to a specific activity of > 1 x 105 units/mg.

    Endotoxin-Niveau

    Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Handhabung

    As with any protein, exposing IL-15 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted IL-15 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

    Haltbarkeit

    24 months
  • Target

    IL-15 (IL15) (Interleukin 15 (IL15))

    Andere Bezeichnung

    IL-15

    Hintergrund

    IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant rat IL-15 is a 13.5 kDa protein consisting of 115 amino acid residues.

    Gen-ID

    25670

    NCBI Accession

    NP_037261

    OMIM

    6981092

    UniProt

    P97604

    Pathways

    JAK-STAT Signalweg, Glycosaminoglycan Metabolic Process
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