VEGF Protein (AA 27-190)

Produktnummer ABIN2181901

Produktdetails

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 27-190

Spezies: Maus

Quelle: HEK-293 Cells

Marke: ActiveMax®

Sequenz: AA 27-190

Produktmerkmale: This protein carries no "tag". The protein has a calculated MW of 19.3 kDa. The protein migrates as 23-25 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.

Reinheit: >95 % as determined by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Güteklasse: HPLC verified

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Handhabung: Please avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Antigendetails

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Andere Bezeichnung: VEGF (VEGF Produkte)

Hintergrund: Vascular endothelial growth factor A (VEGFA) is also known as Vascular permeability factor (VPF). VEGFA belongs to the PDGF/VEGF growth factor family. VEGFA is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. VEGFA is produced by a group of three major isoforms as a result of alternative splicing and if any three isoforms are produced (VEGFA120, VEGFA164, and VEGFA188) then this will not result in vessel defects and death of the full VEGFA knockout in mice.

Molekulargewicht: 19.3 kDa