Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 31-691) (Active) protein (His tag) Protein
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- Target Alle PCSK9 Proteine anzeigen
- PCSK9
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 31-691
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Spezies
- Ratte
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses PCSK9 Protein ist gelabelt mit His tag.
- Sequenz
- AA 31-691
- Produktmerkmale
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 73.2 kDa. The protein migrates as 22 and 66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Reinheit
- >95 % as determined by reduced SDS-PAGE.
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
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Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 31-692) (Active) protein (His tag) Protein
PCSK9 Spezies: Human Wirt: HEK-293 Cells Recombinant >97 % as determined by SDS-PAGE. Active
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 31-692) (Active) protein (His tag,AVI tag,Biotin) ProteinPCSK9 Spezies: Human Wirt: HEK-293 Cells Recombinant >92 % as determined by reduced SDS-PAGE. Active
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 31-692) (Active) protein (Fc Tag) ProteinPCSK9 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 154-686), (AA 31-152) (Active) protein (His tag) ProteinPCSK9 Spezies: Kaninchen Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 31-692) (Active) protein (His tag) ProteinPCSK9 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 30-691) (Active) protein (His tag) ProteinPCSK9 Spezies: Hamster Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 35-694) (Active) protein (His tag) ProteinPCSK9 Spezies: Maus Wirt: HEK-293 Cells Recombinant >97 % as determined by SDS-PAGE. Active
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 35-694) (Active) protein (His tag,AVI tag,Biotin) ProteinPCSK9 Spezies: Maus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 153-692) protein (His tag) ProteinCrystallography grade PCSK9 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) (AA 156-694) protein (His tag) ProteinCrystallography grade PCSK9 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 150 mM NaCl, pH 7.5
- Handhabung
- Please avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- PCSK9
- Andere Bezeichnung
- PCSK9 (PCSK9 Produkte)
- Synonyme
- FH3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9, AI415265, AI747682, Narc1, proprotein convertase subtilisin/kexin type 9, proprotein convertase subtilisin/kexin type 9 L homeolog, PCSK9, pcsk9.L, pcsk9, Pcsk9
- Hintergrund
- Proprotein convertase subtilisin/kexin type 9 (PCSK9), is an enzyme which in humans is encoded by the PCSK9 gene.This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A (EGF-A) domain of the low-density lipoprotein receptor (LDLR), inducing LDLR degradation. PCSK9 may also have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a rare form of autosomal dominant familial hypercholesterolemia (HCHOLA3).
- Molekulargewicht
- 13.9 kDa and 59.3 kDa
- NCBI Accession
- NP_954862
