Interleukin 21 Receptor (IL21R) (AA 20-236) (Active) protein (Fc Tag)

Produktnummer ABIN2181374

Produktdetails

Target: IL21 Receptor (IL21R)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 20-236

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IL21 Receptor Protein ist gelabelt mit Fc Tag.

Sequenz: AA 20-236

Produktmerkmale: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.6 kDa. As a result of glycosylation, the protein migrates as 65-80 kDa under reducing (R) condition, and 130-160 kDa under non-reducing (NR) condition (SDS-PAGE).

Reinheit: >92 % as determined by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 50 mM Tris, 100 mM Glycine, pH 7.5

Handhabung: Please avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Antigendetails

Target: IL21 Receptor (IL21R)

Andere Bezeichnung: IL-21 R (IL21R Produkte)

Synonyme: IL21R, il-21ra.a, CD360, NILR, interleukin 21 receptor, interleukin 21 receptor, tandem duplicate 1, IL21R, il21r.1, Il21r

Hintergrund: Interleukin-21 receptor (IL21R) is also known as CD antigen CD360, Novel interleukin receptor (NILR), is a receptor for interleukin-21 and belongs to the type I cytokine receptor family or type 4 subfamily. IL21R contains two fibronectin type-III domains. IL21R is selectively expressed in lymphoid tissues and most highly expressed in thymus and spleen. IL21R transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells.

Molekulargewicht: 51.6 kDa

Pathways: JAK-STAT Signalweg