IL1R2 Protein (AA 14-343) (Fc Tag)
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- Target Alle IL1R2 Proteine anzeigen
- IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 14-343
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IL1R2 Protein ist gelabelt mit Fc Tag.
- Sequenz
- AA 14-343
- Produktmerkmale
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 64 kDa. The protein migrates as 68-74 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Reinheit
- >95 % as determined by SDS-PAGE.
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL1R2 Protein
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Interleukin 1 Receptor, Type II (IL1R2) (AA 14-343) protein (Fc Tag)
IL1R2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 1 Receptor, Type II (IL1R2) protein (His tag)IL1R2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Interleukin 1 Receptor, Type II (IL1R2) (AA 14-355) protein (His tag)IL1R2 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 Receptor, Type II (IL1R2) protein (Fc Tag)IL1R2 Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 Receptor, Type II (IL1R2) (AA 21-120) protein (GST tag)IL1R2 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 1 Receptor, Type II (IL1R2) (AA 14-343) protein (His tag)IL1R2 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 1 Receptor, Type II (IL1R2) (Active) protein (Fc Tag)IL1R2 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
Interleukin 1 Receptor, Type II (IL1R2) (Active) protein (His tag)IL1R2 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 1 Receptor, Type II (IL1R2) (Active) protein (His tag)IL1R2 Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, pH 7.5
- Handhabung
- Please avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
- Andere Bezeichnung
- IL1R2 /CD121b (IL1R2 Produkte)
- Hintergrund
- Interleukin-1 receptor type 2 (IL1R2) is also known as CD121 antigen-like family member B (CDw121b), IL-1 type II receptor, Interleukin-1 receptor type II, belongs to the interleukin-1 receptor family. Two distinct types of IL1 receptors which are able to bind IL1 specifically have been identified, designated as IL1RI (IL1RA) and IL1RII (IL1RB). IL1R2 is non-signaling receptor for IL1A, IL1B and IL1RN, reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. IL1R2 modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
- Molekulargewicht
- 63.9 kDa
- NCBI Accession
- NP_004624
- Pathways
- NF-kappaB Signalweg
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