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Dipeptidyl-Peptidase 4 (DPP4) (AA 29-766) Protein

DPP4 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN2180980
$451.00
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
  • Target Alle DPP4 Proteine anzeigen
    DPP4
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 29-766
    Spezies
    • 19
    • 5
    • 3
    • 2
    • 1
    Human
    Quelle
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Sequenz
    AA 29-766
    Produktmerkmale
    This protein carries no "tag". The protein has a calculated MW of 85.4 kDa. The protein migrates as 95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    50 mM HEPES, 150 mM NaCl, pH 7.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: 4-8°C for 1 year in lyophilized state 4-8°C for 1 month under sterile conditions after reconstitution -20°C to -70°C for 3 months under sterile conditions after reconstitution
  • Target
    DPP4
    Andere Bezeichnung
    DPPIV (DPP4 Produkte)
    Synonyme
    ADABP, ADCP2, CD26, DPPIV, TP103, MGC81966, MOP9.8, MOP9_8, DPP4, si:ch73-2d23.3, Cd26, Dpp-4, THAM, dipeptidyl peptidase 4, dipeptidyl-peptidase 4 S homeolog, prolyl oligopeptidase family protein, dipeptidyl-peptidase 4, dipeptidylpeptidase 4, DPP4, dpp4.S, AT5G24260, dpp4, Dpp4
    Hintergrund
    Dipeptidyl peptidase-IV (DPPIV) is also known as adenosine deaminase complexing protein 2, DPPIV or CD26 is antigenic enzyme expressed on the surface of most cell types and is associated with immune regulation, signal transduction and apoptosis. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. The substrates of DPPIV are proline (or alanine)-containing peptides and include growth factors, chemokines, neuropeptides, and vasoactive peptides. DPPIV plays a major role in glucose metabolism. It is responsible for the degradation of incretins such as GLP-1. DPPIV plays an important role in tumor biology, and is useful as a marker for various cancers, with its levels either on the cell surface or in the serum increased in some neoplasms and decreased in others. DPPIV also binds the enzyme adenosine deaminase specifically and with high affinity. The significance of this interaction has yet to be established.
    Molekulargewicht
    85.5 kDa
    NCBI Accession
    NP_001926
    Pathways
    Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
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