CD14 (CD14) (AA 20-344) protein (His tag) Protein
- Target Alle CD14 Proteine anzeigen
- AA 20-344
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CD14 Protein ist gelabelt mit His tag.
- AA 20-344
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.6 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- >98 % as determined by SDS-PAGE.
- 0.22 μm filtered
- Less than 1.0 EU per μg by the LAL method.
CD14 (CD14) (AA 20-345) protein (His tag) Protein
Crystallography grade CD14 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WBCD14 (CD14) (AA 20-367) protein (His tag) Protein
Crystallography grade CD14 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WBCD14 (CD14) (AA 16-336) protein (His tag) Protein
Crystallography grade CD14 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
- Nur für Forschungszwecke einsetzbar
- PBS, pH 7.4
- Please avoid repeated freeze-thaw cycles.
- -20 °C
- Informationen zur Lagerung
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
- Andere Bezeichnung
- CD14 (CD14 Produkte)
- CD14 molecule, CD14 antigen, CD14, Cd14
- Cluster of differentiation 14 (CD14), is a cell surface glycoprotein, and is a is a component of the innate immune system. CD14 is a myelomonocytic differentiation antigen preferentially expressed on monocytes, macrophages, and activated granulocytes. CD14 exists in two forms. Either it is anchored into the membrane by a glycosylphosphatidylinositol tail (mCD14) or it appears in a soluble form (sCD14). Soluble CD14 either appears after shedding of mCD14 (48 kDa) or is directly secreted from intracellular vesicles (56 kDa). CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). CD14 has been proposed to be involved in various biological processes, including transportation of other lipids, cell-cell interaction during different immune responses, as well as recognition of apoptotic cells. Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns. CD14+ cells are monocytes that can differentiate into a host of different cells. CD14 has been shown to interact with Lipopolysaccharide-binding protein.
- 35.9 kDa
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades