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AXL Receptor tyrosine Kinase (AXL) (AA 26-449) protein (His tag) Protein

AXL Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN2180607
$275.00
Zzgl. Versandkosten $45.00
Lieferung in 21 bis 31 Werktagen
  • Target Alle AXL Proteine anzeigen
    AXL
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 26-449
    Spezies
    • 16
    • 3
    • 2
    • 1
    • 1
    Human
    Quelle
    • 8
    • 6
    • 3
    • 3
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses AXL Protein ist gelabelt mit His tag.
    Sequenz
    AA 26-449
    Produktmerkmale
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 46.6 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    AXL
    Andere Bezeichnung
    Axl (AXL Produkte)
    Synonyme
    JTK11, UFO, AI323647, Ark, Tyro7, Ufo, AXL receptor tyrosine kinase, Axl receptor tyrosine kinase, AXL, Axl
    Hintergrund
    AXL Receptor Tyrosine Kinase is also known as Tyrosine-protein kinase receptor UFO, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. AXL contains two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. AXL is highly expressed in metastatic colon tumors. AXL is activated by GAS6-binding and subsequent autophosphorylation. AXL is involved in signal transduction from the extracellular matrix into the cytoplasm by binding growth factors, and thus implicated in the stimulation of cell proliferation.
    Molekulargewicht
    46.6 kDa
    Pathways
    RTK Signalweg, Cellular Response to Molecule of Bacterial Origin
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