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KIT Ligand Protein (KITLG) (AA 26-189)

Dieses Recombinant KIT Ligand-Protein wird in Yeast (Pichia pastoris) produziert.
Produktnummer ABIN2018380

Kurzübersicht für KIT Ligand Protein (KITLG) (AA 26-189) (ABIN2018380)

Target

Alle KIT Ligand (KITLG) Proteine anzeigen
KIT Ligand (KITLG)

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 28
  • 17
  • 12
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Maus

Quelle

  • 38
  • 9
  • 8
  • 8
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Yeast (Pichia pastoris)

Reinheit

> 95 % by SDS-PAGE and HPLC analyses.
  • Proteineigenschaft

    AA 26-189

    Produktmerkmale

    ED50 < 10.0 ng/mL, measured by a cell proliferation assay using human TF-1 cells, corresponding to a specific activity of > 1.0x 10^5 units/mg.
    AA 26-189, expressed with an N-terminal Met.

    Endotoxin-Niveau

    < 0.2 EU/μg, determined by LAL method.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstituted in ddH2O at 100 μg/mL.

    Buffer

    Lyophilized after extensive dialysis against 50 mM Tris, pH 8.0.

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Lyophilized recombinant mouse Stem Cell Factor (rmSCF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmSCF should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.

    Haltbarkeit

    6 months
  • Target

    KIT Ligand (KITLG)

    Andere Bezeichnung

    Stem Cell Factor (SCF)

    Hintergrund

    Stem Cell Factor (SCF) is a hematopoietic growth factor that binds to the c-Kit receptor. SCF exerts its activity during the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors. Recombinant mouse Stem Cell Factor (rmSCF) produced in P. pastoris is a single glycosylated polypeptide chain containing 165 amino acids. A fully biologically active molecule, rmSCF has a molecular mass of 18.4 kDa analyzed by reducing SDS-PAGE.
    Synonyms: Stem Cell Factor, c-Kit Ligand, Mast Cell Growth Factor (MGF), Steel Factor

    Molekulargewicht

    18.4kDa, observed by reducing SDS-PAGE.

    UniProt

    P20826

    Pathways

    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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