KIT Ligand Protein (KITLG) (AA 26-189)
Kurzübersicht für KIT Ligand Protein (KITLG) (AA 26-189) (ABIN2018380)
Target
Alle KIT Ligand (KITLG) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 26-189
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Produktmerkmale
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ED50 < 10.0 ng/mL, measured by a cell proliferation assay using human TF-1 cells, corresponding to a specific activity of > 1.0x 10^5 units/mg.
AA 26-189, expressed with an N-terminal Met. -
Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstituted in ddH2O at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against 50 mM Tris, pH 8.0.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Lyophilized recombinant mouse Stem Cell Factor (rmSCF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmSCF should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
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Haltbarkeit
- 6 months
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- KIT Ligand (KITLG)
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Andere Bezeichnung
- Stem Cell Factor (SCF)
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Hintergrund
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Stem Cell Factor (SCF) is a hematopoietic growth factor that binds to the c-Kit receptor. SCF exerts its activity during the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors. Recombinant mouse Stem Cell Factor (rmSCF) produced in P. pastoris is a single glycosylated polypeptide chain containing 165 amino acids. A fully biologically active molecule, rmSCF has a molecular mass of 18.4 kDa analyzed by reducing SDS-PAGE.
Synonyms: Stem Cell Factor, c-Kit Ligand, Mast Cell Growth Factor (MGF), Steel Factor -
Molekulargewicht
- 18.4kDa, observed by reducing SDS-PAGE.
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UniProt
- P20826
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
Target
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