IL-5 Protein (AA 20-132)

Produktnummer ABIN2018130

Recombinant IL-5-Protein exprimiert in CHO Cells.

Kurzübersicht für IL-5 Protein (AA 20-132) (ABIN2018130)

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Ratte

Quelle: CHO Cells

Reinheit: > 95 % as analyzed by SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 20-132

Produktmerkmale: ED50 < 0.5 ng/mL, measured in a proliferation assay using TF-1 Cells.

Endotoxin-Niveau: < 0.2 EU/μg, determined by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Lagerung: -80 °C

Informationen zur Lagerung: Lyophilized recombinant Rat Interleukin-5 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Rat Interleukin-5 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Haltbarkeit: 6 months

Antigendetails

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Andere Bezeichnung: Interleukin-5 (IL-5)

Hintergrund: Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, mediates the activities of eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release.
Synonyms: EDF, BCDFII, TRF

Molekulargewicht: 13-21 kDa, observed by reducing SDS-PAGE.

UniProt: Q08125

Pathways: JAK-STAT Signalweg, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour