Amphiregulin Protein (AREG) (AA 101-198)
Kurzübersicht für Amphiregulin Protein (AREG) (AA 101-198) (ABIN2017667)
Target
Alle Amphiregulin (AREG) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 101-198
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Produktmerkmale
- ED50 < 0.2 ng/mL, measured in a cell proliferation assay using 3T3 cells.
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Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
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Amphiregulin (AREG) (Active) protein
AREG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Amphiregulin (AREG) (AA 101-187) protein (Fc Tag)AREG Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Amphiregulin (AREG) (AA 100-248) protein (Fc Tag)AREG Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Amphiregulin (AREG) (AA 101-198) protein (His tag)AREG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Amphiregulin (AREG) (AA 1-252) protein (GST tag)AREG Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Amphiregulin (AREG) (AA 20-187) protein (Fc Tag)AREG Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Lyophilized recombinant Human Amphiregulin remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Amphiregulin should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Haltbarkeit
- 6 months
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- Amphiregulin (AREG)
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Andere Bezeichnung
- Amphiregulin
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Hintergrund
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Amphiregulin is a member of the EGF family of cytokines, which comprises at least ten proteins including EGF, TGF-alpha, HB-EGF, Epiregulin, Tomoregulin, Neuregulins and the various heregulins. Through the EGF/TGF-alpha receptor, it stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin's extracellular domain is proteolytically processed to release the mature protein.
Synonyms: AR, AREG, Colorectum cell-derived growth factor (CRDGF) -
Molekulargewicht
- 15-20 kDa, observed by reducing SDS-PAGE.
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UniProt
- Q5U026
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Pathways
- RTK Signalweg, EGFR Signaling Pathway
Target
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