Decorin Protein (DCN) (AA 1-359) (GST tag)

Produktnummer ABIN1351201

Dieses Recombinant Decorin-Protein wird in Wheat germ produziert. Es sind 4 Publikationen verfügbar.

Kurzübersicht für Decorin Protein (DCN) (AA 1-359) (GST tag) (ABIN1351201)

Target: Decorin (DCN)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Wheat germ

Applikation: Western Blotting (WB), ELISA, Antibody Array (AA), Affinity Purification (AP)

Produktdetails

Proteineigenschaft: AA 1-359

Aufreinigungstag / Konjugat: Dieses Decorin Protein ist gelabelt mit GST tag.

Verwendungszweck: DCN (Human) Recombinant Protein (P01)

Sequenz: MKATIILLLL AQVSWAGPFQ QRGLFDFMLE DEASGIGPEV PDDRDFEPSL GPVCPFRCQC HLRVVQCSDL GLDKVPKDLP PDTTLLDLQN NKITEIKDGD FKNLKNLHAL ILVNNKISKV SPGAFTPLVK LERLYLSKNQ LKELPEKMPK TLQELRAHEN EITKVRKVTF NGLNQMIVIE LGTNPLKSSG IENGAFQGMK KLSYIRIADT NITSIPQGLP PSLTELHLDG NKISRVDAAS LKGLNNLAKL GLSFNSISAV DNGSLANTPH LRELHLDNNK LTRVPGGLAE HKYIQVVYLH NNNISVVGSS DFCPPGHNTK KASYSGVSLF SNPVQYWEIQ PSTFRCVYVR SAIQLGNYK

Produktmerkmale: Human DCN full-length ORF ( AAH05322, 1 a.a. - 359 a.a.) recombinant protein with GST-tag at N-terminal.

Aufreinigung: in vitro wheat germ expression system

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -80 °C

Informationen zur Lagerung: Best use within three months from the date of receipt of this protein.

Referenzen

Soria-Valles, Gutiérrez-Fernández, Guiu, Mari, Fueyo, Gomis, López-Otín: "The anti-metastatic activity of collagenase-2 in breast cancer cells is mediated by a signaling pathway involving decorin and miR-21." in: Oncogene, Vol. 33, Issue 23, pp. 3054-63, (2014) (PubMed).

Khan, Girish, Lala, Di Guglielmo, Lala: "Decorin is a novel VEGFR-2-binding antagonist for the human extravillous trophoblast." in: Molecular endocrinology (Baltimore, Md.), Vol. 25, Issue 8, pp. 1431-43, (2011) (PubMed).

Ang, Boivin, Williams, Zhao, Abraham, Carmine-Simmen, McManus, Bleackley, Granville: "Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm." in: Cell death & disease, Vol. 2, pp. e209, (2011) (PubMed).

Hiebert, Boivin, Abraham, Pazooki, Zhao, Granville: "Granzyme B contributes to extracellular matrix remodeling and skin aging in apolipoprotein E knockout mice." in: Experimental gerontology, Vol. 46, Issue 6, pp. 489-99, (2011) (PubMed).

Antigendetails

Target: Decorin (DCN)

Andere Bezeichnung: DCN

Hintergrund: Full Gene Name: decorin
Synonyms: CSCD,DSPG2,PG40,PGII,PGS2,SLRR1B

Gen-ID: 1634

Pathways: Glycosaminoglycan Metabolic Process