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KIT Ligand Protein (KITLG)

Dieses Recombinant KIT Ligand-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN1097473

Kurzübersicht für KIT Ligand Protein (KITLG) (ABIN1097473)

Target

Alle KIT Ligand (KITLG) Proteine anzeigen
KIT Ligand (KITLG)

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 28
  • 18
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Human

Quelle

  • 38
  • 9
  • 8
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  • 3
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  • 1
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Escherichia coli (E. coli)

Applikation

Functional Studies (Func)

Reinheit

> 95 % as determined by reducing SDS-PAGE.
  • Verwendungszweck

    Recombinant Human Stem Cell Factor/SCF/c-Kit Ligand

    Sequenz

    MEGICRNRVT NNVKDVTKLV ANLPKDYMIT LKYVPGMDVL PSHCWISEMV VQLSDSLTDL LDKFSNISEG LSNYSIIDKL VNIVDDLVEC VKENSSKDLK KSFKSPEPRL FTPEEFFRIF NRSIDAFKDF VVASETSDCV VSSTLSPEKD SRVSVTKPFM LPPVA

    Produktmerkmale

    Recombinant Human SCF (Stem Cell Factor) produced in E. coli is a single non-glycosylated polypeptide chain containing 165 amino acids with a molecular mass of 18.4 kDa.

    Sterilität

    0.2 μm filtered

    Endotoxin-Niveau

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • Kommentare

    Biological activity: ED50 is less than 2 ng/ml as determined by the dose-dependent stimulation of Human TF-1 cells.Specific Activity of 5.0 x 105 IU/mg.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.0.

    Handhabung

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    Lagerung

    4 °C/-20 °C/-80 °C

    Informationen zur Lagerung

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Haltbarkeit

    3 months
  • Target

    KIT Ligand (KITLG)

    Andere Bezeichnung

    scf

    Hintergrund

    Recombinant Human SCF: Stem Cell Factor is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors.
    Alternative Names: Recombinant Human SCF, Kit Ligand, Mast Cell Growth Factor, MGF, Stem Cell Factor, SCF, c-Kit ligand, KITLG, MGF, SCF

    Molekulargewicht

    18.4 kDa

    UniProt

    P21583

    Pathways

    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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