Cathepsin L Protein (AA 18-333) (His tag)

Produktnummer ABIN1096242

Dieses Recombinant Cathepsin L-Protein wird in Human Cells produziert.

Kurzübersicht für Cathepsin L Protein (AA 18-333) (His tag) (ABIN1096242)

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 18-333

Aufreinigungstag / Konjugat: Dieses Cathepsin L Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Cathepsin L/CTSL (C-6His)

Sequenz: TLTFDHSLEA QWTKWKAMHN RLYGMNEEGW RRAVWEKNVK MIELHNQEYR EGKHSFTMAM NAFGDMTSEE FRQVMNGFQN RKPRKGKVFQ EPLFYEAPRS VDWREKGYVT PVKNQGQCGS CWAFSATGAL EGQMFRKTGR LISLSEQNLV DCSGPQGNEG CNGGLMDYAF QYVQDNGGLD SEESYPYEAT EESCKYNPKY SVANDTGFVD IPKQEKALMK AVATVGPISV AIDAGHESFL FYKEGIYFEP DCSSEDMDHG VLVVGYGFES TESDNNKYWL VKNSWGEEWG MGGYVKMAKD RRNHCGIASA ASYPTVVDHH HHHH

Produktmerkmale:

Recombinant Human Cathepsin L/CTSL (C-6His)

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.5.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Andere Bezeichnung: Cathepsin L

Hintergrund: Recombinant Human Cathepsin L is produced by our mammalian expression system in human cells. The target protein is expressed with the full length sequence of Human Cathepsin L fused with a polyhistidine tag at the C-terminus.
Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins involved in growth regulation. Unlike the precursor forms of other papain family members, the 43 kDa pro-cathepsin L itself is secreted from various cells. Pro-cathepsin L is the major excreted protein of malignantly transformed mouse fibroblasts and is also one of the major acidic cysteine proteases in mammalian cells.

Molekulargewicht: 36.88 kDa

UniProt: P07711

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades