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PRKG1 Proteine

(Protein Kinase, CGMP-Dependent, Type I (PRKG1))
Mammals have three different isoforms of cyclic GMP-dependent protein kinase (Ialpha, Ibeta, and II). These PRKG isoforms act as key mediators of the nitric oxide/cGMP signaling pathway and are important components of many signal transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by alternative transcript splicing. A separate gene on human chromosome 4, PRKG2, encodes the membrane-bound PRKG isoform II. The PRKG1 proteins play a central role in regulating cardiovascular and neuronal functions in addition to relaxing smooth muscle tone, preventing platelet aggregation, and modulating cell growth. This gene is most strongly expressed in all types of smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala. Isoforms Ialpha and Ibeta have identical cGMP-binding and catalytic domains but differ in their leucine/isoleucine zipper and autoinhibitory sequences and therefore differ in their dimerization substrates and kinase enzyme activity. [provided by RefSeq, Sep 2011].

10 Treffer

PRKG1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Produktnummer ABIN1316297
 
PRKG1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Produktnummer ABIN1316295
 
PRKG1 Spezies: Human Wirt: Insektenzellen Recombinant 70 % - 90 % Func Active
Produktnummer ABIN5509120
 
PRKG1 Spezies: Human Wirt: Human Cells Recombinant > 80 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318303
 
PRKG1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Produktnummer ABIN7578994
 
PRKG1 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, PC, Imm
Produktnummer ABIN7408975
 
PRKG1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, PC, Imm
Produktnummer ABIN7399274
 
PRKG1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2713946
 
PRKG1 Spezies: Human, Maus, Ratte Wirt: Escherichia coli (E. coli) Recombinant WB, PC
Produktnummer ABIN2749665
 
PRKG1 Spezies: Human Wirt: Human Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE. WB, SDS, ELISA, MS
Produktnummer ABIN7313308
 
  • Typ Protein
    • Protein
  • Anwendung
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Positive Control (PC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Immunogen (Imm)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Mass Spectrometry (MS)
    • Standard (STD)
  • Reaktivität
    • Human
    • Mouse
    • Rat
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • Human Cells
    • Wheat germ
    • HEK-293 Cells
    • Insect Cells
  • Bindungsspezifität
    • AA 1-686
    • AA 2-686
    • AA 324-671
    • AA 73-170
    • Transcript Variant 2
  • Konjugat
    • His tag
    • GST tag
    • Myc-DYKDDDDK Tag
    • Unkonjugiert
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
    • Frozen
  • Biologische Aktivität
    • Biologically Active
  • Hersteller
    • antibodies-online
    • Cohesion Biosciences
    • FabGennix
    • OriGene

Aliase für PRKG1 Proteine

protein kinase, cGMP-dependent, type Ia (prkg1a) Proteine
protein kinase, cGMP-dependent, type I (PRKG1) Proteine
protein kinase, cGMP-dependent, type I (prkg1) Proteine
protein kinase, cGMP-dependent, type 1 (Prkg1) Proteine
protein kinase, cGMP-dependent, type I (Prkg1) Proteine
1 Proteine
AW125416 Proteine
cGK Proteine
cGk1 Proteine
cGK 1 Proteine
cGK1 Proteine
cGKI Proteine
CGKI Proteine
cGKI-alpha Proteine
cGKI-BETA Proteine
cGKI-beta Proteine
Gm19690 Proteine
PKG Proteine
Pkgi Proteine
prkg1 Proteine
PRKG1B Proteine
Prkg1b Proteine
Prkg1beta Proteine
PRKGR1B Proteine
Prkgr1b Proteine
zgc:63955 Proteine
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