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PPM1F Proteine

(Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008].

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PPM1F Protein (AA 1-452) (His tag)

custom-made PPM1F Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Ppm1f Protein, UniprotID Q8CGA0

3 Abbildungen

Produktnummer ABIN7559321

Details

PPM1F Protein (AA 1-454) (His tag)

custom-made PPM1F Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant PPM1F Protein, UniprotID P49593

3 Abbildungen

Produktnummer ABIN7550864

Details

PPM1F Protein (AA 1-454) (GST tag)

PPM1F Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA

Image no. 1 for Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F) (AA 1-454) protein (GST tag) (ABIN1315912)

1 image

Produktnummer ABIN1315912

Details

PPM1F Protein (AA 1-454) (His tag)

PPM1F Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB

Western Blotting (WB) image for Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F) (AA 1-454) protein (His tag) (ABIN7124670)

1 image

Produktnummer ABIN7124670

Details

PPM1F Protein

PPM1F Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant SDS

Produktnummer ABIN2131260

Details

PPM1F Protein (AA 1-452) (Strep Tag)

custom-made PPM1F Spezies: Maus Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Produktnummer ABIN3125997

Details

PPM1F Protein (AA 1-454) (Strep Tag)

custom-made PPM1F Spezies: Human Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Produktnummer ABIN3086246