PPM1F Produkte
(Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
Kategorien
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008].
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Ausgewählte PPM1F Kategorien
PPM1F Antikörper
High quality antibodies with extensive validation data.
PPM1F Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PPM1F Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7165944
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (4)
Kat. Nr.
ABIN564170
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN392883
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene PPM1F ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6232997
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PPM1F Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315912
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315914
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124670
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PPM1F Produkten
: "Regulation of the multifunctional Ca2+/calmodulin-dependent protein kinase II by the PP2C phosphatase PPM1F in fibroblasts." in: The Journal of biological chemistry, Vol. 279, Issue 23, pp. 24889-98, (2004) (PubMed).: "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages." in: Nature medicine, Vol. 9, Issue 2, pp. 191-7, (2003) (PubMed).
: "The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family." in: Current biology : CB, Vol. 12, Issue 4, pp. 317-21, (2002) (PubMed).
: "The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosis." in: The Journal of biological chemistry, Vol. 276, Issue 47, pp. 44193-202, (2001) (PubMed).
: "Molecular cloning of Ca2+/calmodulin-dependent protein kinase phosphatase." in: Journal of biochemistry, Vol. 125, Issue 6, pp. 1022-8, (1999) (PubMed).
Synonyme und alternative Namen zu PPM1F
protein phosphatase, Mg2+/Mn2+ dependent 1F (PPM1F), protein phosphatase 1F (PP2C domain containing) (Ppm1f), protein phosphatase, Mg2+/Mn2+ dependent, 1F (Ppm1f), 1110021B16Rik, 4933427B07Rik, CAMKP, CaMKPase, FEM-2, hFEM-2, mKIAA0015, Popx2, POPX2Bezeichner auf Proteinebene für PPM1F
- ca(2+)/calmodulin-dependent protein kinase phosphatase
- caM-kinase phosphatase
- calcium/calmodulin-dependent protein kinase phosphatase
- partner of PIX2
- protein phosphatase 1F
- Ca(2+)/calmodulin-dependent protein kinase phosphatase
- CaM-kinase phosphatase
- PP2C phosphatase
- partner of PIX 2
- protein fem-2 homolog
- protein phosphatase 1F (PP2C domain containing)
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